Therapeutic efficacy of chitosan against invasive candidiasis in mice
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چکیده
منابع مشابه
Efficacy of Fluconazole Prophylaxis on Invasive Candidiasis Infection in Extremely Low Birth Weight Neonates
Background: Invasive candidiasis infection is one of the main life-threatening problems for extremely low birth weight (ELBW) neonates who are in the neonatal intensive care unit (NICU). Candidiasis can cause mortality, short-term morbidity, and long-term neurodevelopmental outcome in infected infants who survive. Therefore, since several years ago fluconazole prophylaxis has begun for prematur...
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OBJECTIVE To study the toxicity and activity of two new amphotericin B formulations: poly(epsilon-caprolactone) nanospheres coated with poloxamer 188 (AmB-NP) and mixed micelles with the same surfactant (AmB-MM). MATERIALS AND METHODS The toxicity of these formulations was evaluated in erythrocytes, J774.2 macrophages and LLCPK1 renal cells, as well as in mice. Activity was determined in clin...
متن کاملEfficacy of Spirulina platensis on immune functions in cancer mice with systemic candidiasis
The aim of this study was to investigate the immunomodulatory effects of Spirulina platensis (S.platensis) by measuring the levels of serum interleukin (IL)-4, IL-10, IL-17, tumor necrosis factor(TNF)-α and interferon (IFN)-|γ| in mice suffered from systemic candidiasis and breast cancer. Theaqueous extract of S. platensis was selected for this study. Balb/C female mice were inoculated withCand...
متن کاملSafety, Efficacy, and Exposure–Response of Voriconazole in Pediatric Patients With Invasive Aspergillosis, Invasive Candidiasis or Esophageal Candidiasis
BACKGROUND Data on safety and efficacy of voriconazole for invasive aspergillosis (IA) and invasive candidiasis/esophageal candidiasis (IC/EC) in pediatric patients are limited. METHODS Patients aged 2-<18 years with IA and IC/EC were enrolled in 2 prospective open-label, non-comparative studies of voriconazole. Patients followed dosing regimens based on age, weight and indication, with adjus...
متن کاملInvasive candidiasis: new insights presaging new therapeutic approaches?
The expanding universe of amyloid has revealed an intriguing new galaxy, invasive candidiasis, with the publication by Gilchrist et al in this issue of the Journal. Invasive infection of the gut by Candida albicans is a serious, intractable condition that occurs most commonly but not exclusively in neutropenic patients and for which there is very poorly effective treatment. Gilchrist et al now ...
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ژورنال
عنوان ژورنال: The Journal of Basic & Applied Zoology
سال: 2015
ISSN: 2090-9896
DOI: 10.1016/j.jobaz.2014.12.001